After human experimentation turns Kisaragi into a cyborg, he finds himself pressured by multiple organizations: An undying convent of vampires bent on the conquest of Tokyo, and an immortal order of knights, and a group of Yakuza, sword to avenge the killing of their leader.

I might not have any reason to live, but thats no reason to let them kill me.

Kisaragi will have to use his cyborg-body and his unique blood, as well as anything else he can to make his big escape!!!

(Source: Official Site, translated)