Private detective Hazama Itsuru is hired by Professor Tani to investigate a cyborg parts theft which eventually leads him to meet Sachiko Yokogawa, the original 8 Mans love interest. Living her new life working for the Biotecho Corp., Sachiko finds herself involved with a new 8 Man, who appears after Hazama is fatally wounded by an unknow cyborg. Amidst a violent urban background with cyber-junkies creating chaos around the city, this other 8 Man will fight criminals in a more agressive way.